Institute of Reproductive and Stems Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Science, Central South University, Xiangya Road 88#, Changsha, 410008, Hunan, China. Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410013, Hunan, China. Hunan International Scientific and Technological Cooperation Base of Development and Carcinogenesis, Changsha, 410013, Hunan, China. National Engineering and Research Center of Human Stem Cells, Changsha, 410013, Hunan, China. Institute of Reproductive and Stems Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Science, Central South University, Xiangya Road 88#, Changsha, 410008, Hunan, China. linggf@hotmail.com. Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410013, Hunan, China. linggf@hotmail.com. Hunan International Scientific and Technological Cooperation Base of Development and Carcinogenesis, Changsha, 410013, Hunan, China. linggf@hotmail.com. National Engineering and Research Center of Human Stem Cells, Changsha, 410013, Hunan, China. linggf@hotmail.com. Institute of Reproductive and Stems Cell Engineering, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, School of Basic Medical Science, Central South University, Xiangya Road 88#, Changsha, 410008, Hunan, China. lianghu7@gmail.com. Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-XIANGYA, Changsha, 410013, Hunan, China. lianghu7@gmail.com. Hunan International Scientific and Technological Cooperation Base of Development and Carcinogenesis, Changsha, 410013, Hunan, China. lianghu7@gmail.com. Hunan Normal University School of Medicine, ChangshaHunan, 410013, China. lianghu7@gmail.com.